Exploring Vibration of Effects in Pooled Analyses
Pooled analyses (ie, non-exhaustive quantitative syntheses that pool individual participant data from several independent RCTs exploring...
REPRODUCIBILITY IN THERAPEUTIC RESEARCH
ReiTheR is a meta-research project funded by the Agence Nationale de la Recherche (reference number ANR-17-CE-36-0010-01). Some ancillary projects were supported by Région Bretagne and Fondation pour la Recherche Médicale and are also presented on this website. The group now collaborates with the Committee for Open Science to develop clinical trial data sharing plans. A new project is funded by the French Ministry of Health (Programme Hospitalier de Recherche Clinique: Esketamine for “treatment resistant depression”: an Individual Patient Data Meta-analysis: ESK-T-Dep).
A policy forum
The ReiTheR project outputs can help to define new policies for medical journals: our policy forum "Medical journal requirements for clinical trial data sharing: ripe for improvement" is now out in PLOS Medicine. It proposes an agenda that aims to reform medical journal requirements for clinical trial data sharing.
Essay challenge winner !
Our essay "An open science pathway for drug marketing authorization -Registered drug approval" won the "Reimagine Biomedical Research for a Healthier Future Essay Challenge" sponsored by the Health Research Alliance and PLOS.
A registered report
Our first registered report "Data-sharing and re-analysis for main studies assessed by the European Medicines Agency—a cross-sectional study on European Public Assessment Reports" is now out in BMC Medicine. With the ReITheR project we are studying features associated with reproducibility. + We try to adopt best standards for reproducible science: registered reports represent such a promising standard and we are pleased to have used this new publication format.
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CONTACT
Interested in our research ? To learn more please contact us.
ReITheR / Florian Naudet
Inserm CIC 1414
22 Rue Henri le Guilloux
35000 Rennes