We now have 4 years’ experience of research with ReITheR. In the future, we propose to go further, to develop, implement and test solutions using a meta-research approach. Here are the future research projects we are (or hopefully will be) involved in.
Open Science to Increase Reproducibility in Science (OSIRIS)
While over the past decade many interventions to improve reproducibility have been introduced, targeted at funders, publishers, or individual researchers, only few of them have been empirically tested. OSIRIS aims to fill this gap by systematically gathering knowledge on the underlying drivers, testing effective evidence-based solutions, identifying incentives for reproducibility by stakeholders, and embedding reproducibility in research design.OSIRIS project has received funding from the European Union’s Horizon Europe research and innovation programme under the grant agreement No. 101094725.
Registered drug approvals: an open science pathway for drug approvals and health technology assessments (OPEN&FAIR)
OPEN&FAIR aims to durably reform the way drug regulation and clinical trials are performed, by remodeling clinical trials and their assessment with an open science approach: the registered drug approval pathway. Not funded yet.
Sharing and re-using clinical trial data to maximise impact (SHARE-CTD)
Responsible sharing of clinical trials data holds incredible promises to increase value and decrease waste in medical research. We see a developing field of professional activities that need well educated experts to define and implement best practices. SHARE-CTD aims to train such a new generation of experts in CTDS and will implement specific teachings with a focus on clinical trial transparency and reproducible research practices. SHARE-CTD has received funding from the European Union’s Horizon Europe research and innovation programme under the grant agreement MSCA-2022-DN-01 101120360.
Research Integrity in Biomedical Research (RestoRe)
The objectives of RestoRe are i) to describe problems of scientific integrity in biomedical research within 3 relevant domains (fraudulent studies, conflict of interests between authors and editors and financial conflict of interests), ii) to explore underlying scientific practices to better understand researchers’ behaviours), and iii) to elaborate on any legal and ethical implications. RestoRe has received funding from the French ANR.